NYCgal, If you have money to burn book into Bellagio. Its pretty much the acknowledged "best" and its location can't be beat. Also Its a true destination and it feels like you can sit a table in Fix and watch everyone in Vegas stroll by.

I would take either the MGM or Bellagio

I heard Bellagio was the best when I was last there (10 yrs ago... had a fake ID if you were wondering) but what about the newer ones... Venetian and Wynn?

NYCgal, Venetina and Wynn have their good points, especially the all suite arrangement at the Venetian, but they don't have the location quality. If you wished to try all three, that would be fine, but I would start at Bellagio.

NYC,

Bellagio wasn't there 10 years ago...

Mandalay Bay - THEhotel!

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Bellagio is too expensive. Try a suite in the new Augustus Tower at Caesars. 1/2 of the rooms have views of the Bellagio fountains. Bellagio doesn't appreciate rowdiness, and since you haven't seen each other much, you most likely will get on the crazy side.

Caesars Augustus!

Silly

All the places people are mentioning have spas I think, and my girlfriends and I enjoy getting massages and other luxuries when we go off together. Sometimes they have a package that will save you money or a special "spa tower". You might look in to that.